NMDA receptor antagonist-3

NMDA receptor antagonist-3, a NMDA receptor antagonist, stands out with a remarkable percentage of recovery (40.0%, at 100 μM) and safe toxicological profile in SH-SY5Y and human adipose mesenchymal stem cells.

Product Specifications

CAS Number

[2762181-52-0]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nmda-receptor-antagonist-3.html

Solubility

10 mM in DMSO

Smiles

O=C(CN)N1[C@@H](C2)CC[C@@H]2[C@@]1([H])C(N[C@H](C(O)=O)CC(O)=O)=O

Molecular Formula

C13H19N3O6

Molecular Weight

313.31

References & Citations

[1]Sampaio-Dias IE, et al. Design, Synthesis, and Biological Evaluation of Hybrid Glypromate Analogues Using 2-Azanorbornane as a Prolyl and Pipecolyl Surrogate. ACS Chem Neurosci. 2021 Oct 6;12 (19) :3615-3624.