HA3AR agonist 1
HA3AR agonist 1 is a potent human A3 adenosine receptor (hA3AR) agonist with a Ki value of 2.40 nM.
Product Specifications
CAS Number
2821704-65-6
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ha3ar-agonist-1.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@H](N2C=NC3=C(NC)N=CN=C23)SC[C@H]1N
Molecular Formula
C10H14N6OS
Molecular Weight
266.32
References & Citations
[1]Lee Y, et al. Subtle Chemical Changes Cross the Boundary between Agonist and Antagonist: New A3 Adenosine Receptor Homology Models and Structural Network Analysis Can Predict This Boundary. J Med Chem. 2021 Sep 9;64 (17) :12525-12536.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A3 receptor (A3R)
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