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5-HT7R antagonist 1

5-HT7R antagonist 1 is a G protein-biased antagonist against 5-HT7R (Ki = 6.5 nM) .

Product Specifications

CAS Number

2759919-13-4

UNSPSC

12352005

Target

G protein-coupled Bile Acid Receptor 1

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/5-ht7r-antagonist-1.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC(C2=NNC=C2N3CCCNCC3)=CC=C1.Cl

Molecular Formula

C14H18Cl2N4

Molecular Weight

313.23

References & Citations

[1]Kwag R, et al. Discovery of G Protein-Biased Antagonists against 5-HT7R. J Med Chem. 2021 Sep 23;64 (18) :13766-13779.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT7 Receptor

Frequently Asked Questions

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