Ten01
Product Specifications
UNSPSC Description
Ten01 has 5.0 nM activity against JAK1 kinase.
Target Antigen
JAK
Type
Reference compound
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ten01.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)C1=CN=C(NC=C2)C2=C1C[C@H]3CN(C(NCC(F)(F)F)=O)C[C@@H]3CC
Molecular Weight
422.37
References & Citations
[1]Yu Y, et al. A Novel Scalarized Scaffold Hopping Algorithm with Graph-Based Variational Autoencoder for Discovery of JAK1 Inhibitors. ACS Omega. 2021 Aug 24;6(35):22945-22954.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139649/Ten01-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139649/
Clinical Information
No Development Reported
Curated Selection
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