Ten01
Ten01 has 5.0 nM activity against JAK1 kinase.
Product Specifications
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ten01.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)C1=CN=C(NC=C2)C2=C1C[C@H]3CN(C(NCC(F)(F)F)=O)C[C@@H]3CC
Molecular Formula
C18H20F6N4O
Molecular Weight
422.37
References & Citations
[1]Yu Y, et al. A Novel Scalarized Scaffold Hopping Algorithm with Graph-Based Variational Autoencoder for Discovery of JAK1 Inhibitors. ACS Omega. 2021 Aug 24;6 (35) :22945-22954.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JAK1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6386467-01 0.1 mL
NAP1L2 (Nucleosome Assembly Protein 1-like 2, Brain-specific Protein, X-linked, BPX, MGC26243) (PE)
Ask
View Details 
MBS6386467-02 5x 0.1 mL
NAP1L2 (Nucleosome Assembly Protein 1-like 2, Brain-specific Protein, X-linked, BPX, MGC26243) (PE)
Ask
View Details 