MtDTBS-IN-1
MtDTBS-IN-1 is a particularly potent binder (KD = 57 nM) and inhibitor (Ki = 5 μM) of MtDTBS.
Product Specifications
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mtdtbs-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1CCC[C@H]1C(C(O)=O)C(O)=O)C2=CC=C(C3=NN=NN3)C=C2
Molecular Formula
C16H16N4O5
Molecular Weight
344.32
References & Citations
[1]Schumann NC, et al. Inhibition of Mycobacterium tuberculosis Dethiobiotin Synthase (MtDTBS) : Toward Next-Generation Antituberculosis Agents. ACS Chem Biol. 2021 Nov 19;16 (11) :2339-2347.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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