PTP1B-IN-13
PTP1B-IN-13 is a selective PTP1B inhibitor targeting the allosteric site with an IC50 value of 1.59 μM.
Product Specifications
CAS Number
650621-20-8
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ptp1b-in-13.html
Solubility
10 mM in DMSO
Smiles
O=C(CCC1=CC=CC=C1)NC(NC2=CC=C(S(=O)(NC3=CC=C(C)C(C)=C3)=O)C=C2)=S
Molecular Formula
C24H25N3O3S2
Molecular Weight
467.60
References & Citations
[1]Yang Y, et al. Integrated Approach to Identify Selective PTP1B Inhibitors Targeting the Allosteric Site. J Chem Inf Model. 2021 Sep 27;61 (9) :4720-4732.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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