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PTP1B-IN-13

PTP1B-IN-13 is a selective PTP1B inhibitor targeting the allosteric site with an IC50 value of 1.59 μM.

Product Specifications

CAS Number

650621-20-8

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ptp1b-in-13.html

Solubility

10 mM in DMSO

Smiles

O=C(CCC1=CC=CC=C1)NC(NC2=CC=C(S(=O)(NC3=CC=C(C)C(C)=C3)=O)C=C2)=S

Molecular Formula

C24H25N3O3S2

Molecular Weight

467.60

References & Citations

[1]Yang Y, et al. Integrated Approach to Identify Selective PTP1B Inhibitors Targeting the Allosteric Site. J Chem Inf Model. 2021 Sep 27;61 (9) :4720-4732.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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