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Anticancer agent 11

Anticancer agent 11 is a broad-spectrum anticancer agent that inhibits angiogenesis and induces DNA cross-links.

Product Specifications

CAS Number

[2332936-95-3]

UNSPSC

12352005

Target

DNA Alkylator/Crosslinker

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-11.html

Solubility

10 mM in DMSO

Smiles

OCC1=C2C3=C(C(N(C)C)=NN2C(C)=C1CO)C=C4C=CC=CC4=C3

Molecular Formula

C20H21N3O2

Molecular Weight

335.40

References & Citations

[1]Chen TL, et al. Discovery of Oral Anticancer 1,2-Bis (hydroxymethyl) benzo[g]pyrrolo[2,1-a]phthalazine Hybrids That Inhibit Angiogenesis and Induce DNA Cross-Links. J Med Chem. 2021 Sep 9;64 (17) :12469-12486.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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