Anticancer agent 11
Anticancer agent 11 is a broad-spectrum anticancer agent that inhibits angiogenesis and induces DNA cross-links.
Product Specifications
CAS Number
[2332936-95-3]
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-11.html
Solubility
10 mM in DMSO
Smiles
OCC1=C2C3=C(C(N(C)C)=NN2C(C)=C1CO)C=C4C=CC=CC4=C3
Molecular Formula
C20H21N3O2
Molecular Weight
335.40
References & Citations
[1]Chen TL, et al. Discovery of Oral Anticancer 1,2-Bis (hydroxymethyl) benzo[g]pyrrolo[2,1-a]phthalazine Hybrids That Inhibit Angiogenesis and Induce DNA Cross-Links. J Med Chem. 2021 Sep 9;64 (17) :12469-12486.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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