HIV-1 inhibitor-9

HIV-1 inhibitor-9 is found to be potent inhibitor against the wild-type (WT) HIV-1 strain or multiple NNRTI-resistant strains at low nanomolar levels.

Product Specifications

CAS Number

[2708201-36-7]

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hiv-1-inhibitor-9.html

Solubility

10 mM in DMSO

Smiles

N#CC1=CC=C(NC2=NC(CCCC3)=C3C(OC4=C(C)C=C(C#N)C=C4C)=N2)C=C1

Molecular Formula

C24H21N5O

Molecular Weight

395.46

References & Citations

[1]Huang B, et al. Structure-Based Design and Discovery of Pyridyl-Bearing Fused Bicyclic HIV-1 Inhibitors: Synthesis, Biological Characterization, and Molecular Modeling Studies. J Med Chem. 2021 Sep 23;64 (18) :13604-13621.