HIV-1 inhibitor-9
HIV-1 inhibitor-9 is found to be potent inhibitor against the wild-type (WT) HIV-1 strain or multiple NNRTI-resistant strains at low nanomolar levels.
Product Specifications
CAS Number
[2708201-36-7]
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(NC2=NC(CCCC3)=C3C(OC4=C(C)C=C(C#N)C=C4C)=N2)C=C1
Molecular Formula
C24H21N5O
Molecular Weight
395.46
References & Citations
[1]Huang B, et al. Structure-Based Design and Discovery of Pyridyl-Bearing Fused Bicyclic HIV-1 Inhibitors: Synthesis, Biological Characterization, and Molecular Modeling Studies. J Med Chem. 2021 Sep 23;64 (18) :13604-13621.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
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