Pomalidomide-6-O-CH3
Product Specifications
UNSPSC Description
Pomalidomide-6-O-CH3 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-O-CH3 can be connected to the ligand for protein by a linker to form PROTAC[1].
Target Antigen
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-6-o-ch3.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C(N1C3C(NC(CC3)=O)=O)=O)C(N)=CC(OC)=C2
Molecular Weight
303.27
References & Citations
[1]Andrew J. Phillips, et al. Bromodomain targeting degronimers for target protein degradation. WO2017197056A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139542/Pomalidomide-6-O-CH3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139542/
Clinical Information
No Development Reported
CAS Number
1547163-08-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
ARP33658_P050-Biotin 100 µL
TRIM25 Antibody - C-terminal region: Biotin (ARP33658_P050-Biotin)
Ask
View Details 