Pomalidomide 4'-alkylC3-azide
Pomalidomide 4'-alkylC3-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC3-azide can be used in the synthesis of PROTAC[1].
Product Specifications
CAS Number
2357108-05-3
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-4-alkylc3-azide.html
Solubility
10 mM in DMSO
Smiles
[N-]=[N+]=NCCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
Molecular Formula
C16H16N6O4
Molecular Weight
356.34
References & Citations
[1]Liu H, et al. Construction of an IMiD-based azide library as a kit for PROTAC research. Org Biomol Chem. 2021 Jan 6;19 (1) :166-170.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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