VH 101 phenol-alkylC4-amine (dihydrochloride)
VH 101 phenol-alkylC4-amine dihydrochloride is a von-Hippel-Lindau protein ligand (VHL), and incorporates an E3 ligase ligand plus an alkylC4 linker. VH 101 phenol-alkylC4-amine dihydrochloride can be used for PROTAC research extracted from patent WO2022051326A1.
Product Specifications
CAS Number
[2564467-03-2]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vh-101-phenol-alkylc4-amine-dihydrochloride.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C(C1(CC1)F)N[C@@H](C(C)(C)C)C(N2[C@@H](C[C@H](C2)O)C(NCC3=C(C=C(C4=C(C)N=CS4)C=C3)OCCCCN)=O)=O.Cl.Cl
Molecular Formula
C30H44Cl2FN5O5S
Molecular Weight
676.67
References & Citations
[1]John F. BROGNARD, et al. Lzk‑targeting degraders and methods of use. WO2022051326A1
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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