VH 101 phenol-alkylC6-amine (dihydrochloride)
VH 101 phenol-alkylC6-amine dihydrochloride is a functionalized von-Hippel-Lindau (VHL) protein-ligand that can be used for PROTAC synthesis[1].
Product Specifications
CAS Number
[2564467-16-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vh-101-phenol-alkylc6-amine-dihydrochloride.html
Purity
98.71
Solubility
10 mM in DMSO
Smiles
O=C(C1(CC1)F)N[C@@H](C(C)(C)C)C(N2[C@@H](C[C@H](C2)O)C(NCC3=C(C=C(C4=C(C)N=CS4)C=C3)OCCCCCCN)=O)=O.Cl.Cl
Molecular Formula
C32H48Cl2FN5O5S
Molecular Weight
704.72
Precautions
H302, H315, H319, H335
References & Citations
[1]Gray, et al. Inhibitors and degraders of pip4k protein. WO2022246025A1. 2022-11-24.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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