NHS-Modified MMAF
NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) [1].
Product Specifications
CAS Number
[1404073-10-4]
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nhs-modified-mmaf.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCCCO1)[C@@H](NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCCC(ON3C(CCC3=O)=O)=O)=O)=O)=O)OC)=O)CC4=CNC5=CC=CC=C45
Molecular Formula
C55H86N8O12
Molecular Weight
1051.32
References & Citations
[1]Lerchen HG, et, al. Novel binder-drug conjugates (adcs) and their use. WO2012143499A2.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139325/NHS-Modified-MMAF-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139325/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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