PROTAC IRAK4 degrader-5
PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader extracted from patent US20190192668A1, compound I-171[1].
Product Specifications
CAS Number
2360530-61-4
UNSPSC
12352005
Target
IRAK; PROTACs
Type
Reference compound
Related Pathways
Immunology/Inflammation; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-irak4-degrader-5.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN(C2=CC=C(CNCCOCCOCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)C=C2)C=C1NC(C6=COC(C7=CC(NCC(F)(F)F)=NC=C7)=N6)=O)N
Molecular Formula
C41H40F3N11O9
Molecular Weight
887.82
References & Citations
[1]Mainolfi N, et, al. Irak degraders and uses thereof. US20190192668A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IRAK4
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