S-2E
S-2E is an orally active and noncompetitive HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. S-2E has an anti-hyperlipidemic action. S-2E has the potential for familial hypercholesterolemia and mixed hyperlipidemia research[1][2].
Product Specifications
CAS Number
155730-92-0
UNSPSC
12352005
Target
Acetyl-CoA Carboxylase; HMG-CoA Reductase (HMGCR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/s-2e.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=CC=C(C=C2)C(C)(C)C)C[C@H](C1)COC3=CC=C(C=C3)C(O)=O
Molecular Formula
C22H25NO4
Molecular Weight
367.44
References & Citations
[1]Koichi Ohmori, et al. Anti-hyperlipidemic action of a newly synthesized benzoic acid derivative, S-2E. Eur J Pharmacol. 2003 Jun 13;471 (1) :69-76. |[2]K Ohmori, et al. Effects of a novel antihyperlipidemic agent, S-2E, on the blood lipid abnormalities in homozygous WHHL rabbits. Metabolism. 2004 May;53 (5) :680-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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