Thailanstatin C
Thailanstatin C is a pre-mRNA splicing inhibitor (IC50= 6.84 μM) and antiproliferative agent from Burkholderia thailandensis MSMB43[1].
Product Specifications
CAS Number
1426953-24-3
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thailanstatin-c.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](C[C@H]([C@H](O1)C)NC(/C=C\[C@H](C)OC(C(C)C)=O)=O)[C@@H]1C/C=C(C)/C=C/[C@@H]2[C@H]([C@@](O)(C[C@H](O2)CC(O)=O)CCl)O
Molecular Formula
C30H46ClNO9
Molecular Weight
600.14
References & Citations
[1]Liu X, et al. Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43. J Nat Prod. 2013;76 (4) :685-693.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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