Diguanosine 5′-triphosphate

Diguanosine 5′-triphosphate (Gp3G) is a dinucleoside triphosphates. Diguanosine 5′-triphosphate also is a virus-specific oligonucleotide. Diguanosine 5′-triphosphate is needed for the synthesis of RNA during the transcription process[1][2].

Product Specifications

CAS Number

[6674-45-9]

Product Name Alternative

Gp3G

UNSPSC

12352005

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/diguanosine-5-triphosphate.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](O)[C@H](N(C=N2)C(NC(N)=N3)=C2C3=O)O[C@@H]1COP(OP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C=NC6=C5NC(N)=NC6=O)O4)(O)=O)(O)=O)(O)=O

Molecular Formula

C20H27N10O18P3

Molecular Weight

788.41

References & Citations

[1]M Yamakawa, et al. Priming of reovirus transcription by GppppG and formation of CpG (5') GpC. Proc Natl Acad Sci U S A. 1982 Oct;79 (20) :6142-6.|[2]Emmanuel Klein, et al. Synthesis of enzymatically and chemically non-hydrolyzable analogues of dinucleoside triphosphates Ap (3) A and Gp (3) G. J Org Chem. 2002 Jan 11;67 (1) :146-53.