ACAT-IN-4 (hydrochloride)

ACAT-IN-4 hydrochloride (Example 208) is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor. ACAT-IN-4 hydrochloride inhibits NF-κB mediated transcription[1].

Product Specifications

CAS Number

[199984-46-8]

UNSPSC

12352005

Target

Acyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/acat-in-4-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=S(OC1=C(C(C)C)C=C(OCCCN)C=C1C(C)C)(NC(CC2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)=O.[H]Cl

Molecular Formula

C32H51ClN2O5S

Molecular Weight

611.28

References & Citations

[1]Joseph Anthony Cornicelli, et al. Sulfonylaminocarbonyl derivatives for the treatment of nuclear factor-kappa B mediated diseases and disorders. EP1236468A1.