ACAT-IN-4

ACAT-IN-4 (Example 208) is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor. ACAT-IN-4 inhibits NF-κB mediated transcription[1].

Product Specifications

CAS Number

[454203-56-6]

UNSPSC

12352005

Target

Acyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/acat-in-4.html

Solubility

10 mM in DMSO

Smiles

O=S(OC1=C(C(C)C)C=C(OCCCN)C=C1C(C)C)(NC(CC2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)=O

Molecular Formula

C32H50N2O5S

Molecular Weight

574.81

References & Citations

[1]Joseph Anthony Cornicelli, et al. Sulfonylaminocarbonyl derivatives for the treatment of nuclear factor-kappa B mediated diseases and disorders. EP1236468A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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