TLR7/8 agonist 4 hydroxy-PEG10-acid (hydrochloride)
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugates for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the non-cleavable ADC linker hydroxy-PEG10-acid (HY-133307) [1].
Product Specifications
CAS Number
[2388520-36-1]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tlr7-8-agonist-4-hydroxy-peg10-acid-hydrochloride.html
Purity
98.28
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
CCCCC(NC1=C2C(C=CC(N(CC3)CCN3CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=C2)=N4)=NC1=C4N.[H]Cl
Molecular Formula
C41H69ClN6O12
Molecular Weight
873.47
References & Citations
[1]Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
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Hot
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents
Available Sizes
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