TLR7/8 agonist 4 hydroxy-PEG10-acid
TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugates for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the non-cleavable ADC linker hydroxy-PEG10-acid (HY-133307) [1].
Product Specifications
CAS Number
[2388520-17-8]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tlr7-8-agonist-4-hydroxy-peg10-acid.html
Solubility
10 mM in DMSO
Smiles
CCCCC(NC1=C2C(C=CC(N(CC3)CCN3CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=C2)=N4)=NC1=C4N
Molecular Formula
C41H68N6O12
Molecular Weight
837.01
References & Citations
[1]Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Tissue Inhibitors Of Metalloproteinase 2 (TIMP2) BioAssayTM ELISA Kit (Rat) (Wide Range)
