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Pomalidomide-5-C2-NH2 (hydrochloride)

Pomalidomide-5-C2-NH2 (hydrochloride) is a conjugate of E3 ligase ligand and linker, which can be used for PROTACs synthesis[1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-5-c2-nh2-hydrochloride.html

Purity

99.17

Solubility

10 mM in DMSO

Smiles

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(NCCN)=C3)=O.[H]Cl

Molecular Formula

C15H17ClN4O4

Molecular Weight

352.77

References & Citations

[1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61 (2) :543-575.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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