5-Fluorouridine 5'-O-β-D-galactopyranoside
Product Specifications
UNSPSC Description
5-Fluorouridine 5'-O-β-D-galactopyranoside (5'-O-β-D-galactosyl-5-fluorouridine) is a 5-Fluorouridine proagent. 5-Fluorouridine 5'-O-β-D-galactopyranoside can be converted by the enzyme β-D-galactosidase to the potent antineoplastic agent 5-Fluorouridine[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-fluorouridine-5-o-β-d-galactopyranoside.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@](N2C(NC(C(F)=C2)=O)=O)([H])O[C@@H]([C@H]1O)CO[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO
Molecular Weight
424.33
References & Citations
[1]R Abraham, et al. Conjugates of COL-1 monoclonal antibody and beta-D-galactosidase can specifically kill tumor cells by generation of 5-fluorouridine from the prodrug beta-D-galactosyl-5-fluorouridine. Cell Biophys. 1994;24-25:127-33.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-138943/5-Fluorouridine-5-O-β-D-galactopyranoside-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-138943/
Clinical Information
No Development Reported
CAS Number
149965-92-4
Curated Selection
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