5-Fluorouridine 5'-O-β-D-galactopyranoside
5-Fluorouridine 5'-O-β-D-galactopyranoside (5'-O-β-D-galactosyl-5-fluorouridine) is a 5-Fluorouridine proagent. 5-Fluorouridine 5'-O-β-D-galactopyranoside can be converted by the enzyme β-D-galactosidase to the potent antineoplastic agent 5-Fluorouridine[1].
Product Specifications
CAS Number
149965-92-4
Product Name Alternative
5'-O-β-D-galactosyl-5-fluorouridine
UNSPSC
12352005
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-fluorouridine-5-o-β-d-galactopyranoside.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@](N2C(NC(C(F)=C2)=O)=O)([H])O[C@@H]([C@H]1O)CO[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO
Molecular Formula
C15H21FN2O11
Molecular Weight
424.33
References & Citations
[1]R Abraham, et al. Conjugates of COL-1 monoclonal antibody and beta-D-galactosidase can specifically kill tumor cells by generation of 5-fluorouridine from the prodrug beta-D-galactosyl-5-fluorouridine. Cell Biophys. 1994;24-25:127-33.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940034-100 1x 100 µL
Cytokeratin 8/18 (C-51), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400218-100 1x 100 µL
CD100 (Semaphorin-4D) (A8), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040676-100 1x 100 µL
MUC18 / Mucin 18 / CD146 (OJ79c), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400460-100 1x 100 µL
CD44 Standard (156-3C11), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC882216-100 1x 100 µL
CD50 / ICAM3 (CG106), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details