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Dovitinib (dilactic acid)

Dovitinib (dilactic acid) is an orally active inhibitor of VEGF kinase. Dovitinib (dilactic acid) inhibits receptor tyrosine kinases (RTKs) involved in solid and hematologic cancers and tumor angiogenesis[1].

Product Specifications

CAS Number

852433-84-2

Product Name Alternative

CHIR-258 (dilactic acid) ; TKI258 (dilactic acid)

UNSPSC

12352005

Target

VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dovitinib-dilactic-acid.html

Solubility

DMSO : ≥ 30 mg/mL

Smiles

CC(O)C(O)=O.CC(O)C(O)=O.O=C1NC2=C(C(F)=CC=C2)C(N)=C1C3=NC4=CC=C(N5CCN(C)CC5)C=C4N3

Molecular Formula

C27H33FN6O7

Molecular Weight

572.59

References & Citations

[1]Zhu, S., et al. The Chemical Development of CHIR-258. CHIMIA International Journal for Chemistry, 60 (9), 584–592.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

Frequently Asked Questions

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