AKT-IN-5
AKT-IN-5 (Example 8) is a Akt inhibitor with IC50 values of 450 nM and 400 nM for Akt1 and Akt2, respectively[1].
Product Specifications
CAS Number
[1402608-05-2]
UNSPSC
12352005
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/akt-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN2C(C=C1)=NC(C3=CC=C(C4(N)CCC4)C=C3)=C2C5=CC=CC=C5)O
Molecular Formula
C23H20N4O2
Molecular Weight
384.43
References & Citations
[1]Lars BÄRFACKER, et al. Imidazopyridazines as akt kinase inhibitors. WO2012136776A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Akt1; Akt2
Curated Selection
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