EGFR-IN-15
EGFR-IN-15 (compound I-005) is a EGFR inhibitor with an IC50 of 4 nM. EGFR-IN-15 can be used for oncological diseases research[1].
Product Specifications
CAS Number
[2573869-16-4]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-15.html
Purity
96.21
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@H]1CN2C3=CC(Br)=CC=C3N/C2=N\C(C4=CC(C)=NC(C5=C(N(N=C5)C)OCCC1)=C4)=O
Molecular Formula
C24H25BrN6O2
Molecular Weight
509.40
References & Citations
[1]Harald Engelhardt, et al. New macrocyclic compounds and derivatives as egfr inhibitors. WO2020260252A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1
Available Sizes
Curated Selection
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