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Mal-amido-PEG3-NHS ester

Mal-amido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2055353-77-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-amido-peg3-nhs-ester.html

Solubility

10 mM in DMSO

Smiles

O=C(CCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)ON2C(CCC2=O)=O

Molecular Formula

C20H27N3O10

Molecular Weight

469.44

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-1014.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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