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HM Janelia Fluor® 526, SE

HM Janelia Fluor® 526, SE (HM-JF526 NHS) is a derivative of hydroxymethyl JF526 (HM-JF526) . SMLM (single-molecule localization microscopy) imaging in standard phosphate-buffered saline (pH 7.4) revealed that the HM-JF526 label showed spontaneous blinking behavior throughout the imaging session and did not require short-wavelength activation light[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

Product Specifications

CAS Number

2376841-30-2

Product Name Alternative

HM-JF526 NHS

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/hm-janelia-fluor-526-se.html

Solubility

10 mM in DMSO

Smiles

FC1=C(C=C2OC3=CC(N4CC(C4)(F)F)=C(F)C=C3C5(OCC6=CC=C(C=C56)C(ON7C(CCC7=O)=O)=O)C2=C1)N8CC(C8)(F)F

Molecular Formula

C31H21F6N3O6

Molecular Weight

645.51

References & Citations

[1]Zheng Q, et al. Rational Design of Fluorogenic and Spontaneously Blinking Labels for Super-Resolution Imaging [published correction appears in ACS Cent Sci. 2020 Oct 28;6 (10) :1844]. ACS Cent Sci. 2019;5 (9) :1602-1613.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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