Poly (deoxyadenylic-thymidylic) acid (sodium)
Polydeoxyadenylic-thymidylic acid (Poly (dA:dT) ) sodium is a synthetic DNA polymer. Poly (dA:dT) sodium can be used to determine the activity of bound and free ribonucleic acid polymerase. Poly (dA:dT) sodium is recognized by multiple PRRs (cytosolic DNA sensors (CDS), including cGAS, AIM2, DAI, DDX41, IFI16, and LRRFIP1), and triggers the production of type I interferons. Poly (dA:dT) sodium can be used for the research of cancer and virus infection[1].
Product Specifications
CAS Number
86828-69-5
Product Name Alternative
Poly (dA:dT) sodium
UNSPSC
12352200
Target
AIM2; Cyclic GMP-AMP Synthase
Type
Biochemical Assay Reagents
Related Pathways
Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/poly-deoxyadenylic-thymidylic-acid-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=O)N(C=C1C)[C@](C[C@@H]2O)([H])O[C@@H]2CO[P](O)(O)=O.NC3=C4C(N([C@](C[C@@H]5O)([H])O[C@@H]5CO[P](O)(O)=O)C=N4)=NC=N3.[Na].[x].[x]
Molecular Formula
(C10H15N2O8P.C10H14N5O6P) x.xNa
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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