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Deoxythymidine-5'-triphosphate-13C10,15N2 (dilithium)

Deoxythymidine-5'-triphosphate-13C10,15N2 (dTTP-13C10,15N2) dilithium is 13C and 15N-labeled Deoxythymidine-5'-triphosphate. Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.

Product Specifications

CAS Number

2483830-18-6

Product Name Alternative

DTTP-13C10,15N2 (dilithium)

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/deoxythymidine-5-triphosphate-13c10-15n2-dilithium.html

Solubility

10 mM in DMSO

Smiles

O=[13C]([15N]1[13C@H]2[13CH2][13C@H](O)[13C@@H]([13CH2]OP(O)(OP(OP(O)(O[Li])=O)(O[Li])=O)=O)O2)[15NH][13C]([13C]([13CH3])=[13CH]1)=O

Molecular Formula

13C10H15Li2 15N2O14P3

Molecular Weight

505.95

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975;5 (2) :191-202.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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