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7-Deaza-2',3'-dideoxyadenosine

7-Deaza-2',3'-dideoxyadenosine can be used in the synthesis of oligodeoxyribonucleotides[1].

Product Specifications

CAS Number

[40627-30-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/7-deaza-2-3-dideoxyadenosine.html

Solubility

10 mM in DMSO

Smiles

NC1=NC=NC2=C1C=CN2[C@H]3CC[C@@H](CO)O3

Molecular Formula

C11H14N4O2

Molecular Weight

234.25

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Pauwels R, et, al. Investigations on the anti-HIV activity of 2',3'-dideoxyadenosine analogues with modifications in either the pentose or purine moiety. Potent and selective anti-HIV activity of 2,6-diaminopurine 2',3'-dideoxyriboside. Biochem Pharmacol. 1988 Apr 1;37 (7) :1317-25.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Curated Selection

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