7-TFA-ap-7-Deaza-ddA

7-TFA-ap-7-Deaza-ddA (compound 19c, US20060281100A1), a nucleotide derivative, can be used in the synthesis of thiotriphosphate nucleotide dye terminators which can be used in DNA sequencing reactions[1].

Product Specifications

CAS Number

[114748-71-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/7-tfa-ap-7-deaza-dda.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1CC[C@H](N2C=C(C#CCNC(C(F)(F)F)=O)C3=C(N=CN=C23)N)O1

Molecular Formula

C16H16F3N5O3

Molecular Weight

383.33

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Shen G, et, al. Thiotriphosphate nucleotide dye terminators. US20060281100A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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