7-TFA-ap-7-Deaza-ddG
7-TFA-ap-7-Deaza-ddG (compound 19d, US20060281100A1), a nucleotide derivative, can be used in the synthesis of thiotriphosphate nucleotide dye terminators which can be used in DNA sequencing reactions[1].
Product Specifications
CAS Number
[114748-68-4]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/7-tfa-ap-7-deaza-ddg.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1CC[C@H](N2C(NC(N)=NC3=O)=C3C(C#CCNC(C(F)(F)F)=O)=C2)O1
Molecular Formula
C16H16F3N5O4
Molecular Weight
399.32
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Shen G, et, al. Thiotriphosphate nucleotide dye terminators. US20060281100A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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