NOS-IN-1
NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively[1].
Product Specifications
CAS Number
[165383-72-2]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nos-in-1.html
Purity
98.18
Solubility
10 mM in DMSO
Smiles
NC1=NCCC(C)C1.CC(O)=O
Molecular Formula
C8H16N2O2
Molecular Weight
172.22
Precautions
H315, H319, H335
References & Citations
[1]R K Webber, et al. Substituted 2-iminopiperidines as inhibitors of human nitric oxide synthase isoforms. J Med Chem. 1998 Jan 1;41 (1) :96-101.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
INOS; nNOS
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