Bis- (Mal-PEG3) -PH-N-succinimidyl acetate

Bis- (Mal-PEG3) -PH-N-succinimidyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bis-mal-peg3-ph-n-succinimidyl-acetate.html

Solubility

10 mM in DMSO

Smiles

O=C(ON1C(CCC1=O)=O)C2=CC(OCCOCCOCCN3C(C=CC3=O)=O)=CC(OCCOCCOCCN4C(C=CC4=O)=O)=C2

Molecular Formula

C31H35N3O14

Molecular Weight

673.62

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

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