Pyrroline-5-carboxylate
Pyrroline-5-carboxylate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[2139-03-9]
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pyrroline-5-carboxylate.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NCCC1)O
Molecular Formula
C5H7NO2
Molecular Weight
113.11
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Curated Selection
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