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1,6-Bis (mesyloxy) hexane

16-Bismesyloxyhexane is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

4239-24-1

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1-6-bis-mesyloxy-hexane.html

Purity

90.0

Solubility

10 mM in DMSO

Smiles

CS(=O)(OCCCCCCOS(C)(=O)=O)=O

Molecular Formula

C8H18O6S2

Molecular Weight

274.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker

Available Sizes

Frequently Asked Questions

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