Ethoxyquin dimer

Ethoxyquin dimer is a dimer of Ethoxyquin. Ethoxyquin dimer is an antioxidant. Ethoxyquin dimer can more readily accumulate in liver and adipose tissue compared with Ethoxyquin. Ethoxyquin above 10 mg/kg shows hepatotoxicity in mice[1].

Product Specifications

CAS Number

74681-77-9

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Constitutive Androstane Receptor; Drug Metabolite; Keap1-Nrf2; Orphan Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ethoxyquin-dimer.html

Purity

98.70

Solubility

10 mM in DMSO

Smiles

CC1=CC(C)(C)NC2=C1C=C(OCC)C=C2N3C(C)(C)C=C(C)C4=C3C=CC(OCC)=C4

Molecular Formula

C28H36N2O2

Molecular Weight

432.60

Precautions

H302, H315, H319, H335

References & Citations

[1]Bernhard A, et al. Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice. Food Chem Toxicol. 2018 Aug;118:608-625.