4-Dehydrowithaferin A
4-Dehydrowithaferin A is the analogue of withaferin A. Withaferin A is a withanolide isolated from Withania somnifera. 4-Dehydrowithaferin A has the potential for the research of multiple myeloma[1].
Product Specifications
CAS Number
6850-30-2
Product Name Alternative
4-oxo Withaferin A
UNSPSC
12352005
Target
Drug Derivative
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-dehydrowithaferin-a.html
Solubility
10 mM in DMSO
Smiles
C[C@]([C@](CC[C@@]12C)([H])[C@@]([C@]1([H])CC[C@]2([H])[C@@H]([C@@](OC3=O)([H])CC(C)=C3CO)C)([H])C4)(C5=O)[C@@]6(C(C=C5)=O)[C@]4([H])O6
Molecular Formula
C28H36O6
Molecular Weight
468.58
References & Citations
[1]Freitas Misakyan MF, et al. Structure-Activity Relationships of Withanolides as Antiproliferative Agents for Multiple Myeloma: Comparison of Activity in 2D Models and a 3D Coculture Model. J Nat Prod. 2021;84 (8) :2321-2335.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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