Dansyl-Tyr-Val-Gly (TFA)

Dansyl-Tyr-Val-Gly TFA is a substrate of peptidylglycine monooxygenase (PHM) . Peptidylglycine monooxygenase is an essential enzyme for the posttranslational amidation of neuroendocrine peptides[1].

Product Specifications

CAS Number

[350691-68-8]

UNSPSC

12352005

Target

Amino Acid Derivatives

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dansyl-tyr-val-gly-tfa.html

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](C(C)C)C(NCC(O)=O)=O)=O)NS(=O)(C2=CC=CC3=C2C=CC=C3N(C)C)=O.O=C(O)C(F)(F)F

Molecular Formula

C30H35F3N4O9S

Molecular Weight

684.68

References & Citations

[1]Welch EF, et al. Pre-Steady-State Reactivity of Peptidylglycine Monooxygenase Implicates Ascorbate in Substrate Triggering of the Active Conformer. Biochemistry. 2022 Apr 19;61 (8) :665-677.