Sartorypyrone B
Sartorypyrone B is a 2β-acetoxyl analogue of chevalone C. Sartorypyrone B is yielded from the ethyl acetate extract of the culture of the marine sponge-associated fungus Neosartorya tsunodae (KUFC 9213) . Sartorypyrone B exhibits strong growth inhibitory activity, having GI50s of 17.8, 20.5, and 25.0 μM, respectively, for MCF-7, NCI-H460, and A375-C5. Sartorypyrone B has the potential for the research of breast adenocarcinoma, non-small cell lung cancer, and melanoma diseases[1].
Product Specifications
CAS Number
1452396-11-0
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sartorypyrone-b.html
Solubility
10 mM in DMSO
Smiles
C[C@@]([C@]1([H])C(C)([C@H]2OC(C)=O)C)(C[C@@H]2OC(C)=O)[C@](CC[C@@]34C)([H])[C@]([C@]3([H])CC(C5=O)=C(OC(C)=C5)O4)(CC1)C
Molecular Formula
C30H42O7
Molecular Weight
514.65
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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