Sartorypyrone B

Sartorypyrone B is a 2β-acetoxyl analogue of chevalone C. Sartorypyrone B is yielded from the ethyl acetate extract of the culture of the marine sponge-associated fungus Neosartorya tsunodae (KUFC 9213) . Sartorypyrone B exhibits strong growth inhibitory activity, having GI50s of 17.8, 20.5, and 25.0 μM, respectively, for MCF-7, NCI-H460, and A375-C5. Sartorypyrone B has the potential for the research of breast adenocarcinoma, non-small cell lung cancer, and melanoma diseases[1].

Product Specifications

CAS Number

[1452396-11-0]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sartorypyrone-b.html

Solubility

10 mM in DMSO

Smiles

C[C@@]([C@]1([H])C(C)([C@H]2OC(C)=O)C)(C[C@@H]2OC(C)=O)[C@](CC[C@@]34C)([H])[C@]([C@]3([H])CC(C5=O)=C(OC(C)=C5)O4)(CC1)C

Molecular Formula

C30H42O7

Molecular Weight

514.65

References & Citations

[1]Amnat Eamvijarn, et al. Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213) .