N- (2-Hydroxyethyl) oxamic acid
N- (2-hydroxyethyl) -oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria[1][2].
Product Specifications
CAS Number
5270-73-5
UNSPSC
12352211
Hazard Statement
H302-H312-H332
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/n-2-hydroxyethyl-oxamic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C(NCCO)=O
Molecular Formula
C4H7NO4
Molecular Weight
133.10
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Koch RL, et al. The anaerobic metabolism of metronidazole forms N- (2-hydroxyethyl) -oxamic acid. J Pharmacol Exp Ther. 1979;208 (3) :406-410.|[2]Freeman CD, et al. Metronidazole. A therapeutic review and update. Drugs. 1997;54 (5) :679-708.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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