N- (2-Hydroxyethyl) oxamic acid

N- (2-hydroxyethyl) -oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria[1][2].

Product Specifications

CAS Number

[5270-73-5]

UNSPSC

12352211

Hazard Statement

H302-H312-H332

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/n-2-hydroxyethyl-oxamic-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C(NCCO)=O

Molecular Formula

C4H7NO4

Molecular Weight

133.10

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Koch RL, et al. The anaerobic metabolism of metronidazole forms N- (2-hydroxyethyl) -oxamic acid. J Pharmacol Exp Ther. 1979;208 (3) :406-410.|[2]Freeman CD, et al. Metronidazole. A therapeutic review and update. Drugs. 1997;54 (5) :679-708.