DENV-IN-2
DENV-IN-2 is a potent dengue viral replication inhibitor extracted from patent WO2018215315A1, compound 6AB, has an EC50 of 0.016 nM. DENV-IN-2 shows high potent activity against all four serotypes of the Dengue virus with EC50s ranging from 0.013 to 0.029 nM[1].
Product Specifications
CAS Number
2253675-62-4
UNSPSC
12352005
Target
Dengue Virus; DNA/RNA Synthesis; Flavivirus
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/denv-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1[C@H](COC2=CC(OC)=CC(N[C@@H](C3=CC=C(Cl)C=C3)C(N4CCC5=C4C=C(OC(F)(F)F)C=C5)=O)=C2)C1)O
Molecular Formula
C29H26ClF3N2O6
Molecular Weight
590.97
References & Citations
[1]Jean-François BONFANTI, et al.Substituted indoline derivatives as dengue viral replication inhibitors. WO2018215315A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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