Palvanil

Palvanil is a Capsaicin (HY-10448) analogue, shows strong desensitizing capability against the TRPV1 receptor. Palvanil shows anti-nociceptive and anti-inflammation effects[1][2].

Product Specifications

CAS Number

[69693-13-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

TRP Channel

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/palvanil.html

Purity

98.01

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCCCCCC(NCC1=CC=C(O)C(OC)=C1)=O

Molecular Formula

C24H41NO3

Molecular Weight

391.59

Precautions

H302, H315, H319

References & Citations

[1]Luciano De Petrocellis, et al. N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. Pharmacol Res. 2011 Apr;63 (4) :294-9.|[2]Livio Luongo, et al. Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature. Pharmacol Res. 2012 Sep;66 (3) :243-50.