Longiferone B
Longiferone B is a daucane sesquiterpene, that can be isolated from Boesenbergia longiflora rhizomes. Longiferone B shows anti-inflammatory activity against NO release with an IC50 of 21.0 μM. Longiferone B also suppresses the iNOS and COX-2 mRNA expression[1].
Product Specifications
CAS Number
[1639810-67-5]
UNSPSC
12352211
Target
COX; NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/longiferone-b.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](CC(C(C)=CC2)=O)([H])[C@@H](CC1)C(C)=C
Molecular Formula
C15H22O
Molecular Weight
218.33
References & Citations
[1]Sudsai T, et al. Anti-inflammatory activity of compounds from Boesenbergia longiflora rhizomes. J Ethnopharmacol. 2014 Jun 11;154 (2) :453-61.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2; iNOS
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