Sparsomycin
Sparsomycin is a metabolite of the bacterium Streptomyces sparsogenes. Sparsomycin inhibits protein synthesis in both eukaryotic cells and bacteria. Sparsomycin inhibits the translation extension of ribosome PTC[1].
Product Specifications
CAS Number
[1404-64-4]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/sparsomycin.html
Purity
99.0
Solubility
H2O : 1 mg/mL (ultrasonic; warming)
Smiles
O=C(N[C@@H](CO)C[S@](CSC)=O)/C=C/C(C(N1)=O)=C(NC1=O)C
Molecular Formula
C13H19N3O5S2
Molecular Weight
361.44
References & Citations
[1]Codjo H, et, al. COVID-19: Mechanisms of the Antiviral Activities of Selective Antibiotics Targeting the Human 80S Ribosome. 2021;15:38-52.|[2]Lazaro E, et, al. Interaction of the antibiotic sparsomycin with the ribosome. Antimicrob Agents Chemother. 1991 Jan;35 (1) :10-3.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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